What is Osteopathic Manual Therapy? Osteopathic Manual Therapy focuses on the assessment, diagnosis, and treatment of disorders of the body’s structure, whether it is related to the bones, organs, joints, and nervous system. Osteopathic Manual Therapists use manipulations to the joints or organs and gentle oscillatory movements to correct biomechanical dysfunctions. By restoring proper mechanics to an area, the therapist allows for improved function to reduce pain and to restore normal activity.